Overview
Thin-layer chromatography is an analytical technique that separates chemical compounds by distributing them between a stationary phase coated on a flat surface and a mobile solvent phase, enabling identification and quantification of components in complex mixtures. Research published in Advances in Nanotechnology demonstrates applications of this method across pharmaceutical quality control, natural product analysis, and biochemical investigation. Studies have employed thin-layer chromatography to profile phytochemical constituents in plant extracts, including compounds from Senna occidentalis, Tinospora cordifolia, Jatropha tanjorensis, and Acanthus montanus, supporting both traditional medicine research and bioactivity screening. The technique has proven valuable for detecting adulterants in dietary supplements marketed for sexual enhancement and for separating benzoic esters in pharmaceutical formulations. Additional applications include monitoring transesterification reactions in biodiesel production, analyzing lipid components in neurological tissue fractions, characterizing nucleoside analogues during synthetic chemistry workflows, and assessing membrane lipid alterations following toxicant exposure. These diverse implementations underscore thin-layer chromatography's continued relevance as an accessible, cost-effective separation method for preliminary analysis, reaction monitoring, and quality assessment across pharmaceutical development, natural products chemistry, and biochemical research.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Identification and Quantification of an Adulterant in a Dietary Supplement Marketed for Sexual Enhancement
Glass Chromatography Application: TLC Separation of Benzoic Esters in Pharmaceutical Products
Carbofuran Abrogates the Membrane Ca++-Atpase Activity in Liver: The Role of Cholesterol
Lipid Components in the Dynamin Fraction Prepared from Rat Brain
Antibacterial and Cytotoxicity Activities of Major Compounds from Tinospora cordifolia Willd. Growing on Mangifera indica L.
Evaluation of Anthelmintic Activities of Fractions of Acanthus Montanus (Acanthaceae) on Adult Heligmosomoides Bakeri (Nematoda, Heligmosomatidae)
Effects of Selected Secondary Metabolites in Leaf Extract of Jatropha Tanjorensis on Some Gonadal Hormones in Male Wistar Rats
Waste Clay for Biodiesel Through Base Catalyzed Transesterification of Residual Cotton Seed Oil.
Syntheses of Clofarabine and Related C2′-β-fluorinated Nucleoside Analogues
Synthesis of 2-Chloro-2′-Deoxyadenosine (Cladribine) and New Purine Modified Analogues
Polysaccharide Transglycosylases: A Survey of Assay Methods
How this research is being cited
The 12 articles above have been cited 77 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Journal of Molecular Structure
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2026 · Scientific Reports
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2026 · Microbial Pathogenesis
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2026 · Current Microbiology
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2025 · Applied Biochemistry and Biotechnology
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2025 · Next Nanotechnology
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2025 · Frontiers in Nutrition
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2025 · Chemistry & Biodiversity
A sample of recent works citing this journal's research on Thin-Layer Chromatography, linking to each citing work.