Coronary heart disease (CHD) is a condition in which the coronary arteries supplying the heart muscle become narrowed or blocked, most often by the buildup of atherosclerotic plaque, reducing the flow of oxygen-rich blood to the heart. It is among the leading causes of death worldwide and can manifest as chest pain …
Coronary heart disease (CHD) is a condition in which the coronary arteries supplying the heart muscle become narrowed or blocked, most often by the buildup of atherosclerotic plaque, reducing the flow of oxygen-rich blood to the heart. It is among the leading causes of death worldwide and can manifest as chest pain (angina), heart attack, or heart failure. Understanding and managing CHD draws on cardiology, genetics, nutrition, and lifestyle epidemiology. Research in this area examines genetic susceptibility, including polymorphisms in genes such as those encoding tissue factor and PPAR-alpha and their association with CHD risk in specific populations, alongside molecular mechanisms studied through microRNA-based therapeutic strategies for ischemic heart disease. Clinical work addresses outcomes of interventions such as percutaneous coronary intervention in elderly patients and the recognition of heart failure in primary care. Modifiable risk factors are a major focus, with studies on the effects of involuntary smoking and vaping on the cardiovascular system, the lower prevalence of chronic disease risk factors among vegetarians, oxidative processes and antioxidants in biological aging, and the broader move toward personalized medication and customized nutrition. Reflecting the journal's Bioinformatics And Diabetes orientation, this topic situates coronary heart disease within metabolic health, cardiac function assessment, and data-driven approaches to prevention and treatment.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 53 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Coronary Heart Disease, linking to each citing work.