Overview
Biomarkers in cancer are measurable biological molecules or features that indicate the presence of malignancy, characterize its behavior, or predict response to therapy. They may be DNA, RNA, proteins, metabolites, or histologic and immunohistochemical features detected in tumor tissue or in accessible body fluids such as blood, and they support detection, classification, prognosis, treatment selection, and disease monitoring. Cancer biomarkers are commonly grouped by purpose, distinguishing diagnostic markers that confirm disease, prognostic markers that estimate likely outcome, and predictive markers that anticipate benefit from a particular treatment. The molecular categories under study are diverse. Epigenetic markers, including DNA methylation changes and long non-coding RNAs, are examined in head and neck and other cancers; circulating and tissue microRNAs are evaluated for their links to progression and survival; and protein and proliferation markers assessed by immunoassay or immunohistochemistry, such as those quantifying mitotic activity, inform grading. Research in this area also encompasses immunogenomic and proteomic profiling, bioinformatic analysis of disease-associated signatures, and platforms for rigorous biomarker development and validation. A central concern is analytical and clinical validity, ensuring that a candidate marker is reproducible, specific, and meaningfully connected to patient outcomes. By translating tumor biology into quantifiable signals, biomarkers underpin earlier detection and more precise, individualized cancer care.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Epigenetic Biomarkers in Head and Neck Cancer
Avant Garde Alleviation -Cancer Immunotherapy
Dynamic MicroRNA-Expression in Plasma of Melanoma Patients Correlates With Progression, PD-L1 Status and Overall Survival
Long Non-Coding RNAs Emerging as Potential Epigenetic Biomarkers for Tobacco and/or Alcohol-Induced Head and Neck Cancer
Molecular Biomarkers: A Brief Review
The Current Immunoassays and Emerging Immunogenomic Approaches for Immunomonitoring Cancer and Infectious Diseases
Human Proteome Project and Current Bioinformatics Status in Disease Diagnosis and Treatment
A Summary of Circular RNAs in Alzheimer's Disease
A Cancer Theory: The Central Nervous System’s Adaptive Changes Make Chronic Diseases Incurable
Content of Copper, Iron, Iodine, Rubidium, Strontium and Zinc in Thyroid Malignant Nodules and Thyroid Tissue adjacent to Nodules
Comparison of Phosphohistone H3 Immunohistochemical Staining, Ki-67, and H&E Mitotic Count in Invasive Breast Carcinoma
How this research is being cited
The 12 articles above have been cited 28 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Human Gene
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Ambivalent Copper: Mechanistically Distinct Immune Effects Driving Innovation in Cancer Nanomedicine2026 · Pharmaceutics
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2026 · Gene Reports
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2024 · Food Analytical Methods
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2024 · Food Analytical Methods
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Maria Constantin et al. · 2024 · Frontiers in Oncology
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2024 · Biomedical Research and Therapy
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2023 · Medical Oncology
A sample of recent works citing this journal's research on Biomarkers in Cancer, linking to each citing work.