Overview
Human papillomavirus (HPV) is a non-enveloped, double-stranded DNA virus of the Papillomaviridae family that infects cutaneous and mucosal epithelium, with more than two hundred genotypes classified by oncogenic potential. Low-risk types such as HPV-6 and HPV-11 cause anogenital warts, whereas high-risk types, notably HPV-16 and HPV-18, drive virtually all cervical cancers and a substantial share of vulvar, vaginal, anal, penile, and oropharyngeal malignancies. Oncogenesis proceeds through persistent infection and integration of the viral genome, with the E6 and E7 oncoproteins inactivating the p53 and retinoblastoma tumor-suppressor pathways, producing the dysplastic progression detectable as cervical intraepithelial neoplasia. Diagnostic and prognostic correlates include Pap smear cytology and immunohistochemical markers such as p16/INK4a and Ki-67 that distinguish transforming from benign lesions. Research in this area examines the role of HPV in virus-induced carcinogenesis, cervical screening uptake and its determinants across diverse populations, abnormal Pap-smear prevalence, intraepithelial lesion evaluation, and links to head-and-neck cancer epigenetics. The journal publishes peer-reviewed studies addressing cervical cytology, screening determinants among under-served and refugee women, and the molecular pathology of HPV-associated disease, situating prevention, early detection, and the wider landscape of sexually transmitted infection within Cervical Cancer control.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Cervical Cancer with The Active And Stable PI3K/MTOR/AKT Pathway In Azerbaijan Patients
Cervico-Vaginal Smear Abnormalities in a Patient with Pemphigus Vulgaris
The Prevalence of Abnormal Cervical Pap Smears in Women with Morbid Obesity in Dubai, United Arab Emirates
Syphilis and Beyond: A Comprehensive Analysis of Associated Infections and Comorbidities in a Five-Year Retrospective Study in the United Arab Emirates (2018-2022)
P16/INK4a and KI-67 Evaluation of Intraepithelial and Benign Cervical Lesions at the University College Hospital, Ibadan - A Retrospective Immunohistochemically Study
Long Non-Coding RNAs Emerging as Potential Epigenetic Biomarkers for Tobacco and/or Alcohol-Induced Head and Neck Cancer
Epigenetic Biomarkers in Head and Neck Cancer
The Impact of Public Financing, Economic Growth, and Corruption on Immunization Performance: Evidence from 37 Sub-Saharan African Countries
One Out of Five Women Practiced Cervical Cancer Screening in Felege Hiwot Referral Hospital, Amhara, North West Ethiopia
How this research is being cited
The 12 articles above have been cited 19 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · BMC Public Health
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2026 · Gene Reports
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Maria Constantin et al. · 2024 · Frontiers in Oncology
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2024 · Biomedical Research and Therapy
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2023 · Ibnosina Journal of Medicine and Biomedical Sciences
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2023 · Ibnosina Journal of Medicine and Biomedical Sciences
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2023 · Medical Oncology
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S. Kurevlev et al. · 2023 · Head and Neck Tumors (HNT)
A sample of recent works citing this journal's research on Hpv, linking to each citing work.