Chromatin is the macromolecular complex of DNA and associated proteins, principally histones, that packages the eukaryotic genome within the nucleus. Its fundamental repeating unit, the nucleosome, organizes DNA into higher-order structures that range from accessible euchromatin to compact heterochromatin, and dynam…
Chromatin is the macromolecular complex of DNA and associated proteins, principally histones, that packages the eukaryotic genome within the nucleus. Its fundamental repeating unit, the nucleosome, organizes DNA into higher-order structures that range from accessible euchromatin to compact heterochromatin, and dynamic remodeling, together with histone modifications and DNA methylation, governs the accessibility of genes to the transcriptional machinery. Through this regulation chromatin controls when and where genes are expressed, enabling cell differentiation, development, and adaptive responses, while its dysregulation contributes to disease. Research relevant to this area includes epigenetic and gene-regulatory mechanisms in skeletal-muscle satellite-cell senescence involving microRNAs and signaling axes, transcription-factor binding-site analysis of regulatory single-nucleotide polymorphisms in disease and high-altitude adaptation, RNA-binding protein biology, Wnt signaling in oligodendrocyte development, molecular control of human embryonic development, and microRNA-based regulation of gene expression. The journal publishes peer-reviewed work, grouped here under DNA And RNA Research, addressing chromatin organization, epigenetic regulation, transcriptional control, and gene-expression mechanisms, connecting studies of histone- and DNA-level regulation, transcription factors, and non-coding RNAs to the understanding of how genome packaging and remodeling shape cellular function, development, and disease.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 74 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Chromatin, linking to each citing work.