Overview
Enzymology in drug discovery is the study of Enzymes, biological catalysts that drive the chemical reactions of living cells, and their use as targets and tools in developing new medicines. Many drugs work by inhibiting or modulating specific Enzymes, so understanding enzyme structure, catalytic mechanism, kinetics and regulation is central to identifying promising targets, screening candidate compounds and predicting how a drug will affect metabolism. Enzymology also informs how drugs themselves are processed in the body, since metabolic Enzymes determine their activation, breakdown and clearance. As a journal focused on Enzymes, this title's scope covers enzyme structure and function, catalysis, kinetics and the many roles Enzymes play in biochemistry and biotechnology, including their application in pharmaceutical research. This page gathers peer-reviewed, open-access research relevant to enzymology in drug discovery and the broader study of how Enzymes serve as targets, biomarkers and tools in the design and development of therapeutic agents.
Research published in this journal
1 peer-reviewed article, ranked by relevance. Each links to its DOI.