Overview
Blood flow is the movement of blood through the circulatory system, driven by the pressure gradient generated by cardiac contraction and governed by vascular resistance, vessel caliber, and the rheological properties of blood. By the principles relating flow to perfusion pressure and resistance, regional flow is continuously adjusted to match tissue metabolic demand, a regulation achieved through neural, myogenic, and metabolic mechanisms acting on vascular smooth muscle. Adequate flow ensures delivery of oxygen and nutrients and removal of metabolic waste, and its impairment underlies ischemic injury across organ systems. In the brain, cerebral blood flow is tightly controlled by neurovascular coupling, in which neuronal and astrocytic signaling matches local perfusion to activity, and by cerebrovascular reactivity, the capacity of vessels to dilate or constrict in response to stimuli such as carbon dioxide; disturbances are studied in headache, multiple sclerosis, stroke, and vascular malformations, and are amenable to endovascular interventions such as embolization. Hemodynamic modeling, including analysis of particle deposition and flow patterns in coronary and other vessels, further informs understanding of atherosclerosis and thrombosis. The journal publishes peer-reviewed research on vascular and cerebrovascular hemodynamics, neurovascular regulation, perfusion-related pathology, and the modeling and intervention of disturbed blood flow.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Modeling of the Deposition of Low-Density Lipoprotein Particles inside an Ideal Geometry of the Heart Coronary Arteries
Two-Phase Lung Damage Mechanisms For COVID-19 Disease, and Driving Force and Selectivity in Leukecyte Recruitment and Migration
Brain Hemodynamics and Cerebrovascular Reactivity in Patients with Tension-Type Headache
Evidence that N-acetylaspartylglutamate is the Astrocyte-Targeted Neurovascular Coupling Agent that Regulates Slow Tonic Control of Brain Blood Flow
The Evolution of Fetal Surgery
Embolization for Perimedullary Arteriovenous Fistulae: Pioneering Experience in Peru
Neurovascular Reactivity after Repeated Attacks in Patients with Multiple Sclerosis
Review: Non-Invasive Continuous Blood Glucose Measurement Techniques
Toward Better Care for Sickle Cell Disease in Nigeria: A Review of Challenges and Interventions
Laboratory Tests Used in the Diagnosis of Immune Thrombocytopenia and General Treatment Approaches
Feasibility of Detecting Brain Areas Involved in Extreme Breath-Hold Diving
How this research is being cited
The 12 articles above have been cited 124 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Psychiatry Neurology and Medical Psychology
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2025 · Moscow University Chemistry Bulletin
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2025 · Natural Product Research
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S. D. Varfolomeev et al. · 2025 · Moscow University Chemistry Bulletin
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María Ortuño et al. · 2025 · NeuroImage
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B. Bravi et al. · 2025 · Brain, behavior, and immunity
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A KINETIC MODEL OF THE GLUTAMATERGIC SYNAPSE FUNCTIONING - A KEY SYNAPTIC CONTACT IN THE HUMAN BRAINS. D. Varfolomeev et al. · 2025 · Lomonosov chemistry journal
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2025 · Engineering Science Letter
A sample of recent works citing this journal's research on Blood Flow, linking to each citing work.