Research Topic · Peer-Reviewed

Suppressor Genes

Suppressor genes, more fully known as tumor suppressor genes, are genes whose normal function is to restrain cell growth, repair DNA, or trigger programmed cell death, thereby preventing the uncontrolled proliferation that leads to cancer. When both copies of such a gene are lost or inactivated through mutation, the…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 24× across the literature 🔖 ISSN 2372-6601 🗓 Reviewed July 2026

Overview

Suppressor genes, more fully known as tumor suppressor genes, are genes whose normal function is to restrain cell growth, repair DNA, or trigger programmed cell death, thereby preventing the uncontrolled proliferation that leads to cancer. When both copies of such a gene are lost or inactivated through mutation, the cell loses this protective control, contributing to malignant transformation. Tumor suppressor genes work in opposition to oncogenes, and the study of their mutations is central to understanding cancer development, diagnosis, and targeted treatment. Within Hematology and Oncology Research, work relevant to suppressor genes includes an article on the role of genes in tumor formation, which addresses the genetic control of malignant transformation, and a functional, structural, and contextual analysis of a variant of uncertain significance in BRCA1, a well-established tumor suppressor gene. Related research on the genetic and molecular characteristics of meningioma pathogenesis and on molecular diagnosis in cancer reflects the broader study of the genes that govern tumor behavior. This page gathers peer-reviewed, open-access research relevant to tumor suppressor genes and the genetic basis of cancer.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2019

Genes in Tumor Formation

Riede IsoldeCorresponding author
Independent Cancer Research, Im Amann 7, Ueberlingen D-88662.
Exact topic Hematology and Oncology Research Cited by 2 doi:10.14302/issn.2372-6601.jhor-19-2986
2015

Epigenetics and Nutrition

Lundstrom KennethCorresponding author
PanTherapeuitcs, Rue des Remparts 4, CH1095 Lutry, Switzerland
Exact topic International Journal of Nutrition Cited by 2 doi:10.14302/issn.2379-7835.ijn-14-603

How this research is being cited

The 12 articles above have been cited 24 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Suppressor Genes, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Hematology and Oncology Research (ISSN 2372-6601).

Journal editorial board
Jayadev Manikkam Umakanthan · United States Shuaiying Cui · United States Benedetto Sacchetti · Italy

This page summarises published research for orientation; it is not medical or professional advice.