Overview
Antibiotic resistance is the capacity of bacteria to survive and proliferate in the presence of antimicrobial drugs that would otherwise inhibit or kill them. It arises through genetic mutation and the horizontal transfer of resistance determinants on plasmids, transposons, and integrons, and is propagated by selective pressure from antibiotic exposure in clinical and agricultural settings. The principal biochemical mechanisms include enzymatic inactivation of the drug, such as the beta-lactamases and the extended-spectrum and carbapenem-hydrolyzing enzymes; modification or protection of the drug target; reduced membrane permeability; and active efflux. Clinically important resistant phenotypes include carbapenem-resistant Enterobacterales such as Klebsiella pneumoniae, methicillin-resistant Staphylococcus aureus, and multidrug-resistant uropathogens, which compromise the treatment of common and life-threatening infections. Detection relies on phenotypic susceptibility testing and molecular assays, including real-time PCR for resistance genes, while containment depends on antimicrobial stewardship, surveillance, infection prevention, and rational prescribing. The research reflected here spans susceptibility patterns in hospital pathogens, prescribing practices and stewardship across primary and tertiary care, resistance in vulnerable populations, and the interplay between resistance, surgical site infection, and other co-circulating diseases. The journal publishes peer-reviewed studies on the epidemiology, mechanisms, and clinical management of antimicrobial resistance.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Growing Threat Increased Carbapenem-Resistance among Klebsiella pneumoniae; Antibiotic Susceptibility Pattern of Klebsiella pneumoniae in a Tertiary Care Hospital
Knowledge, Attitudes and Practices of Prescribers towards Antimicrobial Stewardship at Hospitals in Khartoum State - Sudan
Antibiotic-Resistant Urinary Tract Infection in a Bahamian Woman: A Case Report
Antibiotic Prescribing Practices for Upper Respiratory Tract Infection Among Clinical Officers at Kiambu County
Morpho-biochemical Identification and Antimicrobial Susceptibility Testing of Bacterial Isolates from Chicken Eggs in District Faisalabad
The Development and Evaluation of A Multiplex Real-Time PCR Assay for the Detection of ESBL Genes in Urinary Tract Infections
Malaria: A Driving Force to the Emergence and the Global Spread of Antibiotics Resistance
Surgical Site Infections: A Still Ongoing Challenge
Investigation of Antimicrobial Activity of the Extracts of the Leaves, Stembark and Root of Allanblackia floribunda: An Alternative Paradigm Shift Outcome.
Ni Hao from the New Editor of the IJANR
How this research is being cited
The 12 articles above have been cited 52 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Infection
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2026 · Antibiotics
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Stefano Cavalli et al. · 2025 · Animals
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Lidya Hafidzah Putri et al. · 2025 · JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
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2025 · Animals
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2025 · PLOS One
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2025 · Frontiers in Microbiology
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2025 · Open Forum Infectious Diseases
A sample of recent works citing this journal's research on Antibiotic Resistance, linking to each citing work.