Research Topic · Peer-Reviewed

Hiv-1

HIV-1 is the predominant type of human immunodeficiency virus and is responsible for the majority of HIV infections and the global AIDS pandemic. A lentivirus of the retrovirus family, it carries a single-stranded RNA genome and the enzymes reverse transcriptase, integrase, and protease, which mediate conversion of …

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 18× across the literature 🔖 ISSN 2994-6743 🗓 Reviewed July 2026

Overview

HIV-1 is the predominant type of human immunodeficiency virus and is responsible for the majority of HIV infections and the global AIDS pandemic. A lentivirus of the retrovirus family, it carries a single-stranded RNA genome and the enzymes reverse transcriptase, integrase, and protease, which mediate conversion of viral RNA to DNA, integration into the host genome, and maturation of new virions; these enzymes are also principal targets of antiretroviral drugs. HIV-1 enters CD4-positive T cells and macrophages via the CD4 receptor and chemokine co-receptors, and its high replication and mutation rates underlie immune evasion, drug resistance, and substantial genetic diversity among groups and subtypes. Transmission occurs through sexual contact, blood, and from mother to child, and progressive depletion of CD4 cells leads to immunodeficiency. Research spans molecular targets, immune responses, and therapeutic and preventive strategies. The subject matter examined in this area includes HLA-E-restricted HIV-1-specific immune responses and T-cell vaccination, docking studies of HIV-1 reverse transcriptase and protease with plant-derived compounds, immunological effects of phytochemical consumption in HIV-1-seropositive individuals, the proposal that phytochemicals may arrest HIV-1 progression, antioxidant capacity and CD4 counts in treated patients, and adherence to pre-exposure prophylaxis. The journal publishes peer-reviewed research on HIV-1 virology, immunology, and clinical management.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2014

Phytochemicals May Arrest HIV-1 Progression

Sharma B.Corresponding author
Department of Biochemistry, Faculty of Science,
Exact topic Clinical Research In HIV AIDS And Prevention Cited by 5 doi:10.14302/issn.2324-7339.jcrhap-13-edt.1.3

How this research is being cited

The 12 articles above have been cited 18 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Hiv-1, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Sexually Transmitted Diseases (ISSN 2994-6743).

Journal editorial board
Jennifer Cunningham-Erves · United States Bassem Refaat · Saudi Arabia Andrea Palicelli · Italy

This page summarises published research for orientation; it is not medical or professional advice.