Research Topic · Peer-Reviewed

Clinical Transplantation

Clinical transplantation is the medical practice of transferring organs, tissues, or cells from a donor to a recipient to replace function lost to disease or organ failure. It encompasses solid-Organ Transplantation, including kidney, heart, lung, and liver, as well as tissue and cell grafts, and it offers life-savi…

Curated from this journal's research 📚 9 peer-reviewed articles cited Cited 19× across the literature 🔖 ISSN 2576-9359 🗓 Reviewed July 2026

Overview

Clinical transplantation is the medical practice of transferring organs, tissues, or cells from a donor to a recipient to replace function lost to disease or organ failure. It encompasses solid-Organ Transplantation, including kidney, heart, lung, and liver, as well as tissue and cell grafts, and it offers life-saving or life-improving treatment for conditions such as end-stage organ failure. Successful transplantation depends on managing the recipient's immune response to non-self tissue, since the immune system recognizes and attacks allografts; immunosuppressive therapy is therefore central, and approaches are increasingly individualized, as illustrated by the use of genetic profiling in patients with acute renal rejection to tailor immunosuppression. The field addresses the diagnosis and management of post-transplant complications, including rejection assessed by biopsy and imaging, infection and malignancy arising under immunosuppression, and organ-specific problems following lung, heart, and kidney transplantation. Donation raises distinctive ethical and policy questions, encompassing the evaluation of living donors, donor health and protection, and debates over incentives and the prohibition of organ sale. Beyond conventional grafting, regenerative strategies using stem cells and differentiation factors explore the restoration of tissue function. Integrating surgery, immunology, ethics, and long-term clinical care, clinical transplantation seeks to restore function and prolong life while balancing the benefits of grafting against the risks of immunosuppression and the moral complexities of donation.

Research published in this journal

9 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 9 articles above have been cited 19 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Clinical Transplantation, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Organ Transplantation (ISSN 2576-9359).

Journal editorial board
Francesca Diomede · Italy Luca Peruzzotti-Jametti · United Kingdom Karolina Golab · United States

This page summarises published research for orientation; it is not medical or professional advice.