Post-transplant complications are the medical problems that arise after solid-Organ Transplantation and that threaten graft survival and recipient health, while their management constitutes a defining component of long-term transplant care. Complications are commonly grouped by mechanism and timing: immunological ev…
Post-transplant complications are the medical problems that arise after solid-Organ Transplantation and that threaten graft survival and recipient health, while their management constitutes a defining component of long-term transplant care. Complications are commonly grouped by mechanism and timing: immunological events including acute and chronic rejection; surgical and vascular problems such as delayed graft function influenced by intraoperative haemodynamics; infectious complications stemming from immunosuppression; and the toxicities and secondary conditions that accompany long-term therapy, including persistent pain, cardiovascular sequelae such as constrictive pericarditis after heart transplantation, and malignancies including skin cancers in immunosuppressed recipients. Effective management depends on early and accurate detection, in which non-invasive imaging such as Doppler ultrasonography is compared against biopsy for evaluating graft dysfunction, allowing timely distinction between rejection, ischaemic injury, and other causes. Immunosuppressive regimens must be balanced to prevent rejection while limiting infection, malignancy, and drug toxicity, and pharmacogenomic profiling, for example single-nucleotide polymorphism analysis in renal recipients, is being explored to personalize therapy. Beyond the clinical sphere, the field also engages ethical and policy dimensions of organ donation, including living-donor evaluation and protection. By integrating surveillance, individualized immunosuppression, and prompt treatment of complications, post-transplant management seeks to maximize graft longevity, minimize morbidity, and improve survival and quality of life after transplantation.
8 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 8 articles above have been cited 21 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Post-transplant Complications and Management, linking to each citing work.