Research Topic · Peer-Reviewed

Headache

Headache is one of the most common neurological symptoms, encompassing primary disorders in which the headache is the condition itself—such as tension-type, migraine, and cluster headache—and secondary headaches arising from an underlying cause such as vascular, structural, or inflammatory disease. Its mechanisms in…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 24× across the literature 🔖 ISSN 2694-1201 🗓 Reviewed July 2026

Overview

Headache is one of the most common neurological symptoms, encompassing primary disorders in which the headache is the condition itself—such as tension-type, migraine, and cluster headache—and secondary headaches arising from an underlying cause such as vascular, structural, or inflammatory disease. Its mechanisms involve trigeminovascular activation, altered cerebral hemodynamics and reactivity, muscular and nociceptive pathways, and central pain processing, with triggers including stress, sleep disturbance, dehydration, and environmental factors. Accurate classification distinguishes benign primary headache from secondary causes that require specific investigation and treatment. Research in related neurological areas examines brain hemodynamics and cerebrovascular reactivity in tension-type headache, occipital neuralgia and its surgical decompression, sacral injection experience, and the headache and neurological manifestations of conditions such as lacunar infarction, posterior reversible encephalopathy syndrome, chiasmal lesions, and neurosarcoidosis. Studies also address self-medication practices, the historical use of blinding in neurological trials, and headache in the context of broader systemic and neuropsychiatric disease. Methods include clinical case series, hemodynamic and imaging studies, and reviews. By separating primary headache disorders from secondary causes, this field guides diagnosis and targeted management. The journal publishes peer-reviewed research on the mechanisms, diagnosis, and treatment of headache and related neurological disorders.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 24 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Headache, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Spine and Neuroscience (ISSN 2694-1201).

Journal editorial board
Barbara Poletti · Italy Ian James Martins · Australia Domenico Chirchiglia · Italy

This page summarises published research for orientation; it is not medical or professional advice.