Polycystic Ovarian Syndrome

Overview

Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder of women of reproductive age, characterized by a combination of ovulatory dysfunction, clinical or biochemical hyperandrogenism, and polycystic ovarian morphology on ultrasound. Diagnosis generally requires at least two of these three features after excluding other causes. The condition arises from interacting hormonal disturbances in which the ovaries produce excess androgens and ovulation becomes irregular or absent, leading to infrequent or absent menstruation and reduced fertility. Hyperandrogenism manifests in features such as hirsutism, acne, and altered anthropometric profiles, while disrupted folliculogenesis underlies the characteristic ovarian appearance. Insulin resistance and compensatory hyperinsulinemia are central to the pathophysiology of many women with PCOS, linking the syndrome to obesity, dyslipidemia, and an elevated long-term risk of type 2 diabetes and other metabolic complications. Because of this, evaluation often includes assessment of body composition, glucose metabolism, and hormonal markers such as estradiol. Management is individualized and addresses the dominant concerns, whether menstrual regulation, fertility, or metabolic risk, and combines lifestyle modification with pharmacological and, where appropriate, nutritional or supplement-based interventions aimed at improving insulin sensitivity and androgen-related symptoms. Research continues to examine dietary and supplementary approaches, ovulation-induction strategies, and the broader reproductive and metabolic consequences of the syndrome, reflecting its complex and heterogeneous nature.

Research published in this journal

5 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 5 articles above have been cited 2 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Oct 2025.

• Retrospective Investigation of IVF Cycle Parameters Likely to Affect Low Oocyte Maturation Rates
  2022 · Türk Üreme Tıbbı ve Cerrahisi Dergisi
• Measurement of Melatonin in serum and follicular in infertile women as an indicator of Pregnancy Rate
  Nebras M. Hamed et al. · 2020 ·

A sample of recent works citing this journal's research on Polycystic Ovarian Syndrome, linking to each citing work.

This page summarises published research for orientation; it is not medical or professional advice.

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