2018
Overview
Adp-ribosylation is a post-translational modification of proteins where the enzyme ADP-ribosyl transferase utilizes a molecule of NAD+ to place an adenosine diphosphate ribose group on a protein. This process is relevant to many vital cellular processes, including DNA repair, chromatin remodeling, organelle biogenesis and metabolism regulation. Adp-ribosylation is also an important mechanism for viral pathogens to subvert the host. By influencing the structure and/or activity of host proteins, ADP-ribosylation can regulate a variety of physiological processes, from differentiation to metabolism. As such, it is an important research target for elucidating the mechanisms of various diseases and identifying potential therapeutic targets.
Research published in this journal
1 peer-reviewed article, ranked by relevance. Each links to its DOI.
How this research is being cited
The 1 article above has been cited 1 time in the scholarly literature. Citation data via OpenAlex and Crossref, updated Oct 2025.
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2018 · Journal of Proteomics and Genomics research
A sample of recent works citing this journal's research on Adp-ribosylation, linking to each citing work.