Research Topic · Peer-Reviewed

Citrulline

Citrulline is an amino acid, often referred to as a “non-essential” amino acid because the body can produce it. It is a key molecule involved in the cycling of the amino acid arginine, which is important for the body to produce nitric oxide, a molecule involved in vasodilation (widening of the blood vessels). Becaus…

📚 0 peer-reviewed articles cited 🗓 Reviewed June 2026

Overview

Citrulline is an amino acid, often referred to as a “non-essential” amino acid because the body can produce it. It is a key molecule involved in the cycling of the amino acid arginine, which is important for the body to produce nitric oxide, a molecule involved in vasodilation (widening of the blood vessels). Because of this, supplementation with citrulline is often used to improve exercise performance and heart health. Citrulline has also been shown to help reduce fatigue, mental stress, and enhance cognitive performance. It is available in a variety of supplement forms, including capsule, powder, tablet, and liquid.

Research published in this journal

No peer-reviewed research on this exact topic has been published in International Journal of Amino Acids yet. Browse the journal →

Editorial oversight

Curated from peer-reviewed research published in International Journal of Amino Acids.

Journal editorial board
Nicolas Inguimbert · France

This page summarises published research for orientation; it is not medical or professional advice.