These instructions outline how to prepare and submit manuscripts to IPJ. The journal publishes physiology research spanning cellular mechanisms, organ systems, integrative biology, and clinical translation. Submissions should emphasize reproducible methods, validated evidence, and clear reporting.

Authors are responsible for ensuring accuracy, completeness, and adherence to ethical standards.

• Original research articles with validated physiological outcomes
• Review articles and systematic reviews
• Methods and tools papers with benchmark results
• Short communications and technical notes
• Perspective pieces on physiology applications

• Title page with author affiliations and corresponding author contact
• Structured abstract with objectives, methods, results, and conclusions
• Introduction with background and physiology rationale
• Methods detailing study design, measurements, and controls
• Results with validation metrics and statistical analysis
• Discussion outlining implications and limitations
• Data availability statement and references

Provide clear descriptions of measurement protocols, instrumentation, and laboratory conditions when applicable. Include validation datasets and explain how physiological outcomes were quantified.

• Specify participant characteristics or model details
• Describe sampling timing, intervention protocols, and controls
• Report laboratory environments or clinical settings
• Include replication and statistical approaches

Authors must include a data availability statement describing where data and code can be accessed. Deposit datasets in reliable repositories and provide persistent identifiers when available.

• Provide repository links and accession numbers
• Share code or provide detailed workflow descriptions
• Document data preprocessing and quality checks
• Explain any access restrictions or embargoes

Manuscripts involving animals or human data must include appropriate ethics approvals. Authors must disclose conflicts of interest and funding sources.

• CONSORT for randomized trials
• STROBE for observational studies
• PRISMA for systematic reviews
• Domain specific physiology reporting standards when applicable

IPJ uses single blind peer review. Reviewers evaluate study rigor, data quality, and clarity of reporting. Initial decisions are typically issued within two to four weeks depending on reviewer availability.

Accepted manuscripts move to production for copyediting, proof review, and DOI registration. Articles are published under CC BY 4.0 to support open access reuse with attribution.

Authors should review proofs promptly to confirm accuracy of figures, tables, and metadata.

APCs are applied after acceptance and cover peer review management, production, and archiving services. Partial waivers may be available for eligible authors. Contact the editorial office for guidance.

• Scope alignment confirmed
• Specimen identification and sampling details documented
• Data availability statement included
• Validation results reported
• Cover letter prepared with scope summary

For questions about formatting or submission steps, contact [email protected].

• Describe participant or model characteristics in detail, including sex, age, and inclusion criteria when applicable.
• Report experimental protocols with enough detail to allow replication across laboratories.
• Provide calibration details for physiological measurement devices and instrumentation.
• State primary endpoints and physiological outcomes clearly before presenting results.
• Include normalization methods for physiological signals such as heart rate, VO2, or blood pressure.
• Explain how environmental conditions such as temperature, altitude, or humidity were controlled.
• For cellular physiology studies, report culture conditions, passage numbers, and media composition.
• Describe anesthesia, analgesia, and monitoring protocols for animal or clinical studies.
• Report statistical models, effect sizes, and confidence intervals for key outcomes.
• Clarify how baseline measurements were obtained and how changes over time were calculated.
• Include information on randomization, blinding, and allocation procedures when applicable.
• Document compliance with ethical approvals and informed consent for human studies.
• Provide reference ranges or normative values used to interpret physiological data.
• Describe sample processing steps for blood, tissue, or biofluid assays.
• If imaging is used, report acquisition parameters, resolution, and analysis software.
• For exercise physiology, report workload, intensity, and recovery protocols in detail.
• Specify timing of measurements relative to interventions, meals, or circadian cycles.
• Discuss limitations related to sample size, heterogeneity, or measurement variability.
• Explain how confounders such as medications, diet, or comorbidities were addressed.
• Provide clear definitions for physiological indices or composite scores used.
• Include quality control procedures for assays, sensors, and data cleaning.
• Report adverse events or unexpected findings relevant to physiological safety.
• Describe translational relevance to clinical practice or public health where appropriate.
• If multi-omic data are used, provide accession numbers and processing workflows.
• State whether data sharing is restricted and provide access pathways when needed.
• Include a short statement on reproducibility and data availability commitments.
• For renal or cardiovascular studies, report diagnostic criteria and staging methods.
• When using animal models, specify strain, housing, and welfare monitoring procedures.
• Describe dose-response protocols for pharmacological or hormonal interventions.
• Provide a concise summary of mechanistic implications supported by the data.
• Report software versions used for signal processing or statistical analysis.
• Include sensitivity analyses or robustness checks when applicable.
• Explain how missing data were handled and report imputation methods if used.
• For integrative physiology, describe how multi-system measures were synchronized.
• Describe electrode placement, sampling frequency, and filtering methods for bioelectrical signals.
• Report spirometry or pulmonary function test standards and reference equations applied.
• Include heart rate variability metrics and clarify time-domain versus frequency-domain analyses.
• Describe hemodynamic measurement techniques and calibration checks for pressure devices.
• When using wearable sensors, report validation studies and device accuracy limits.
• Provide details on dietary controls or fasting status for metabolic assessments.
• State whether sex-specific analyses were performed and justify aggregation when applicable.
• Report power calculations or justification for sample sizes in mechanistic studies.
• Clarify interpretation thresholds for biomarkers, assays, or physiological indices.
• Describe intervention adherence monitoring and protocol deviations when relevant.
• Provide context for clinical relevance by linking physiological changes to outcomes.
• Include pharmacological dosing schedules, route of administration, and washout periods.
• Explain how circadian or diurnal variation was controlled or modeled.
• Include a structured abstract with clear objectives, methods, results, and conclusions to support rapid editorial screening.
• Use SI units throughout and define all abbreviations on first use to maintain clarity for international readers.
• Provide figure legends that explain experimental context, sample sizes, and statistical annotations without requiring cross reference.
• Tables should be editable and include clear headings, units, and footnotes describing statistical tests.
• Confirm that all references include DOIs where available and match the in text citations exactly.
• Disclose funding sources, grant numbers, and any potential conflicts of interest in the manuscript.
• Provide statements describing ethics approvals, permits, and adherence to human or animal research guidelines.
• When reporting multistage studies, describe sampling coverage, exclusions, and attrition to support reproducibility.
• Include a brief limitations statement that addresses study design boundaries and generalizability.
• Supplementary files should be labeled clearly and referenced in the main text for reviewer navigation.
• Ensure the cover letter summarizes novelty, scope alignment, and key methodological strengths.
• Describe how raw data and code can be accessed, including repository links and accession numbers.
• Provide consent statements when human participants are involved.
• State whether preprints exist and disclose any prior dissemination of the findings.

IPJ is committed to rigorous, transparent publishing in physiology research. We emphasize reproducible methods, clear reporting of experimental protocols, and ethical compliance across all article types.

The editorial office supports authors, editors, and reviewers with clear guidance and responsive communication. For questions about scope or workflow, contact [email protected].

We encourage continuous improvement in reporting practices and share updates that help the community maintain high standards in human and comparative physiology.